⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101567 | 1.00 | — | — | |
| SCHEMBL15829440 | 1.00 | — | — | |
| SCHEMBL16299977 | 1.00 | — | — | |
| SCHEMBL1515575 | 1.00 | — | — | |
| SCHEMBL1515508 | 1.00 | — | — | |
| SCHEMBL1516163 | 1.00 | — | — | |
| SCHEMBL62747 | 0.83 | — | — | |
| SCHEMBL87331 | 0.83 | — | — | |
| SCHEMBL21027179 | 0.81 | — | — | |
| SCHEMBL1780491 | 0.79 | KMT2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016085941-A1 | PROCESSES FOR THE PREPARATION OF CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | claimed |
| EP-0003666-B1 | OXABICYCLO 3.1.0 HEXANES USEFUL IN THE PRODUCTION OF CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATE COMPOUNDS | FMC Corporation (US) | 1983-04-06 | — | — | EP | claimed |
| EP-4680609-A1 | KRAS MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20260008789-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-12421254-B2 | KRAS modulators and uses thereof | QUANTA THERAPEUTICS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20250243222-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| WO-2025106905-A1 | COMBINATION THERAPIES WITH A KRAS MODULATOR AND AN IMMUNOMODULATOR INHIBITOR | QUANTA THERAPEUTICS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2025106901-A1 | COMBINATION CANCER THERAPIES WITH A KRAS MODULATOR AND AN RTK-MAPK PATHWAY INHIBITOR | QUANTA THERAPEUTICS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4532494-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119604501-A | Pyrimidine-based modulators and uses thereof | 光达治疗公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20250051365-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| US-20020016492-A1 | Process for preparing 3-hydroxymethyl-4-(aryl or heterocyclic)-cyclopentanones | MERCK SHARP & DOHME CORP. | 2002-02-07 | — | — | US | disclosed |
| US-5439874-A | Preemergence, postemergence herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| EP-0581132-A2 | Substituted Bicyclo[3.1.0]hexanes and their use as herbicide | BAYER AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-4658043-A | Ethers of pantolactone | ROUSSEL UCLAF (FR) | 1987-04-14 | — | — | US | disclosed |
| US-4540797-A | Process for resolution of chiral alcohols or phenols or chiral lactonic compounds | ROUSSEL UCLAF (FR) | 1985-09-10 | — | — | US | disclosed |
| US-4374257-A | Novel ethers containing a lactone group and a chiral atom | ROUSSEL UCLAF (FR) | 1983-02-15 | — | — | US | disclosed |
| EP-0023454-A2 | Process for the preparation of 6,6-dimethyl-4-hydroxy-3-oxabicyclo(3.1.0)hexan-2-one and its ethers of all possible stereoisomeric forms | ROUSSEL-UCLAF (FR) | 1981-02-04 | — | — | EP | disclosed |
| US-4064258-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3987087-A | ANTI-ULCER, NASAL PATENCY, WOUND HEALING, LABOR INDUCEMENT | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |