Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13781104 | 0.91 | PDK2 (0.43) | PDK2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL364863 | 0.91 | PDK2 (0.43) | PDK2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15131520 | 0.88 | PDK2 (0.37) | PDK2PTPN1CNR2CNR1 | |
| SCHEMBL13781093 | 0.88 | PDK2 (0.49) | PDK2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL13781028 | 0.88 | PDK2 (0.49) | PDK2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL12699648 | 0.87 | — | — | |
| SCHEMBL13781057 | 0.86 | PDK2 (0.46) | PDK2KDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL19723627 | 0.85 | LMNA (0.41) | PDK2MAPTCNR2 | |
| SCHEMBL13781092 | 0.85 | PDK2 (0.39) | PDK2KDM4EMAPTCNR2CNR1 | |
| SCHEMBL13781091 | 0.84 | PDK2 (0.39) | PDK2KDM4EMAPTCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-9236571-B2 | Polymer materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-9236571-B2 | Polymer materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| EP-2787053-A1 | Polymeric materials | Merck Patent GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130187096-A1 | POLYMER MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-07-25 | — | — | US | disclosed |
| US-20130187096-A1 | POLYMER MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-07-25 | — | — | US | disclosed |
| WO-2012007102-A1 | POLYMER MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |