Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.40 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.40 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155702 | 0.84 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL14763820 | 0.84 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL23279541 | 0.77 | TSHR (0.44) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL2234953 | 0.77 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL21848157 | 0.76 | TSHR (0.67) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL10127440 | 0.76 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL13246484 | 0.76 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL112613 | 0.75 | AOC3 (0.46) | TSHRCA1CA2CA9ALDH1A1 | |
| SCHEMBL12056408 | 0.75 | TSHR (0.54) | TSHRCA1CA2CA7CA9 | |
| Ethylbenzene SCHEMBL2127915 | 0.75 | TP53 (0.56) | TSHRALDH1A1HTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | NOF CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | F12, FGB, F13B | TSHR 4253/4885CA1 1057/4885CA2 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.