FGB

Fibrinogen beta chain · P02675 · FGB on Sugi Atlas →

3,572 patent compounds predicted against FGB, 2,790 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4397430	0.51	2/20
SCHEMBL595621	0.50	2/20
SCHEMBL487001	0.49	2/20
Ammonia Solution, Strong (SCHEMBL6046897)	0.48	2/20
SCHEMBL2482880	0.43	2/20
SCHEMBL3266102	0.42	2/20
SCHEMBL124078	0.41	2/20
Hematoxylin (SCHEMBL1747)	1.00	1/20
Hematoxylin (SCHEMBL19654)	1.00	1/20
Sanguinarium (SCHEMBL123241)	1.00	1/20
Quinocide (SCHEMBL707955)	1.00	1/20
Haematoxylin (SCHEMBL1784957)	1.00	1/20
SCHEMBL2303569	1.00	1/20
Quinocide (SCHEMBL157174)	0.98	1/20
Hematoxylin (SCHEMBL22203)	0.97	1/20
Sanguinarium (SCHEMBL43290)	0.97	1/20
Hematoxylin (SCHEMBL2635384)	0.97	1/20
Hematoxylin (SCHEMBL4954328)	0.97	1/20
Hematoxylin (SCHEMBL4954735)	0.97	1/20
Sanguinarium (SCHEMBL3222766)	0.95	1/20

Clinical trials — most relevant to FGB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section	PHASE4	COMPLETED
Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography	PHASE4	UNKNOWN
Use of Tranexamic Acid in Blepharoplasties	PHASE3	WITHDRAWN
Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER)	PHASE3	COMPLETED
Human Fibrinogen Concentrate (FGTW) in Pediatric Patients With Congenital Fibrinogen Deficiency	PHASE2/PHASE3	COMPLETED
Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock	PHASE2/PHASE3	COMPLETED
Study of CRP, Ferritine and D-Dimer in Covid-19 Patients Admitted To Respiratory ICU in Assuit University Hospitals	nan	UNKNOWN
Hemodynamic Changes in Acute Ischaemic Stroke Patients	nan	UNKNOWN
Are Uterine Fibroids Pro-thrombotic?	nan	ACTIVE_NOT_RECRUITING
Heparin Management During Cardiopulmonary Bypass in Children	nan	COMPLETED
Mechanisms of Pro-Thrombosis in Diabetes Mellitus -- Ancillary to BARI 2D	nan	COMPLETED
Chinese Community Inpatient Thromboembolism	nan	UNKNOWN
Thromboelastometry Guided DIC Prevention After Cesarean Section in Pregnant Women With Placenta Previa	nan	UNKNOWN
Metabolism of Fibrinogen and Apolipoprotein B-100 in Childhood Obesity and Cardiovascular Disease	nan	COMPLETED
Implementation of an Empiric Transfusion Bundle for Out of Hospital Patients With Haemorrhagic Shock	nan	RECRUITING
Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease.	nan	COMPLETED
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass.	nan	COMPLETED
Point of Care Fibrinogen Measurement in Trauma Patients in the Emergency Department	nan	RECRUITING
Pregnancy and Fibrin Clot Properties	nan	RECRUITING
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.	nan	RECRUITING
Efficacy of Injection Platelet-rich Fibrin(I-PRF) in Accelerate Alignment and Leveling	nan	COMPLETED
Shock Index To DEtect Low Plasma Fibrinogen In Trauma (SIDE)	nan	COMPLETED
The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty	nan	UNKNOWN
Pre-hospital Administration of Fibrinogen in Trauma-Induced Coagulopathy	nan	NOT_YET_RECRUITING
Determination of Fibrin Activity in Plasma on STA-R® Prototype	nan	COMPLETED
Intra-graft Coagulation Events in Clinical Renal Transplantation and Delayed Graft Function	nan	UNKNOWN
Coagulation After Intravenous Methylprednisolone Administration	nan	COMPLETED
Nutritional Habits, and Coronavirus Disease 2019 (COVID-19) Outcome	nan	UNKNOWN
Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography	nan	UNKNOWN
Changes in Measured Plasma Volume, Glycocalyx and Atrial Natriuretic Peptide During Anaesthesia	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a FGB binder may also engage these)

Protein	Name	Similarity
Q8K0E8	—	1.000	Q8K0E8 →
Q8VCM7	—	1.000	Q8VCM7 →
P17634	—	1.000	P17634 →
P02676	—	0.998	P02676 →
P14480	—	0.997	P14480 →
Q1RMR1	—	0.997	Q1RMR1 →
Q02020	—	0.997	Q02020 →
P04115	—	0.996	P04115 →
P02679	—	0.996	P02679 →
Q640P2	—	0.995	Q640P2 →
P02680	—	0.995	P02680 →
Q5XK91	—	0.995	Q5XK91 →
Q14314	—	0.995	Q14314 →
Q29RY7	—	0.995	Q29RY7 →
Q5EA66	—	0.995	Q5EA66 →
Q6AX44	—	0.995	Q6AX44 →
Q86XS5	—	0.994	Q86XS5 →
P12804	—	0.993	P12804 →
O43827	—	0.993	O43827 →
P12799	—	0.993	P12799 →
P02678	—	0.993	P02678 →
O95841	—	0.993	O95841 →
Q5M8C6	—	0.992	Q5M8C6 →
Q0P4P2	—	0.991	Q0P4P2 →
Q9BDY7	—	0.990	Q9BDY7 →
P33573	—	0.990	P33573 →
O35462	—	0.990	O35462 →
Q9R045	—	0.990	Q9R045 →
Q60FC1	—	0.990	Q60FC1 →
O35608	—	0.990	O35608 →