Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14522983 | 0.90 | GAA (0.40) | GAAHTTKMT2A | |
| SCHEMBL14280274 | 0.86 | ALOX15 (0.41) | GAAALOX15KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14315016 | 0.83 | GAA (0.36) | GAAHTTKMT2AALDH1A1 | |
| SCHEMBL7877418 | 0.77 | GAA (0.43) | GAAHTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL272468 | 0.77 | GAA (0.47) | GAAHTTALOX15KMT2AL3MBTL1 | |
| Butane SCHEMBL10595891 | 0.75 | GAA (0.43) | GAAHTTALOX15KMT2AL3MBTL1 | |
| SCHEMBL7873193 | 0.74 | GAA (0.41) | GAAHTTALOX15KMT2AL3MBTL1 | |
| SCHEMBL4408313 | 0.72 | GAA (0.43) | GAAHTTALOX15KMT2AL3MBTL1 | |
| SCHEMBL7877415 | 0.72 | SMYD3 (0.42) | GAAHTTALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL1150065 | 0.72 | GAA (0.46) | GAAHTTALOX15KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429723-B1 | TREATING EFFECTS OF EXCESSIVE REACTIVE OXYGEN SPECIES | SYNZYME TECHNOLOGIES LLC (US) | 2012-05-02 | — | — | EP | disclosed |
| US-7229629-B2 | Carboxylate-gated-nitroxide (CGN) compounds and compositions and methods of use thereof | SYNZYME TECHNOLOGIES, LLC (US) | 2007-06-12 | — | — | US | disclosed |
| US-7229629-B2 | Carboxylate-gated-nitroxide (CGN) compounds and compositions and methods of use thereof | SYNZYME TECHNOLOGIES, LLC (US) | 2007-06-12 | — | — | US | disclosed |