SCHEMBL1005261

SCHEMBL1005261

CCCc1ccc(C)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.61
CNR2 P34972 1/20 0.61
HTT P42858 2/20 0.50
NPC1 O15118 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALOX5 P09917 2/20 0.47
TSHR P16473 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
DRD2 P14416 1/20 0.47
NFKB1 P19838 1/20 0.47
DRD1 P21728 1/20 0.47
DRD4 P21917 1/20 0.47
DRD5 P21918 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1A P35348 1/20 0.47
ADRA1B P35368 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034797 0.89 ALOX15 (0.50) MAPK1ALOX5TSHRCYP2D6DRD2
SCHEMBL1004694 0.88 NPC1 (0.68) CNR1CNR2HTTNPC1HPGD
SCHEMBL3617672 0.84 PPARA (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL8590804 0.84 PPARA (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL10067551 0.84 PPARA (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL11554693 0.84 PPARA (0.61) HTTNPC1HPGDMAPK1RAB9A
Potassium SCHEMBL30435596 0.83 PPARA (0.59) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL332894 0.83 CNR1 (0.67) CNR1CNR2ALOX5TSHRCYP3A4
SCHEMBL8400508 0.83 IGF1R (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL10626367 0.83 MAPT (0.65) HPGDMAPK1NPSR1ALOX5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021127612-A1 BIOMASS-BASED PESTICIDES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2021-06-24 WO claimed
WO-2014001056-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2014-01-03 WO claimed
EP-1418892-A1 SYNERGISTIC MIXED POLOXAMER SYSTEMS FOR THE SOLUBILISATION OF DRUGS Maelor Pharmaceuticals Limited (GB) 2004-05-19 EP claimed
CN-1488664-A Vibration damping material composition 株式会社泰特克斯 2004-04-14 CN claimed
WO-2003017976-A1 SYNERGISTIC MIXED POLOXAMER SYSTEMS FOR THE SOLUBILISATION OF DRUGS MAELOR PHARMACEUTICALS LIMITED (GB) 2003-03-06 WO claimed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4322927-A1 NOVEL USE DSM IP Assets B.V. (NL) 2024-02-21 EP disclosed
CN-117229495-A Polyphenylene ether, method for producing the same, thermosetting composition, prepreg, and laminate 旭化成株式会社 2023-12-15 CN disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
US-20230117370-A1 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS OREGON STATE UNIVERSITY (US) 2023-04-20 US disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
WO-2003017976-A1 SYNERGISTIC MIXED POLOXAMER SYSTEMS FOR THE SOLUBILISATION OF DRUGS MAELOR PHARMACEUTICALS LIMITED (GB) 2003-03-06 WO disclosed
WO-2001015680-A9 COMPOSITION FOR TREATMENT OF INFECTIONS OF HUMANS AND ANIMALS BEEK GLOBAL NINKOV L L C VAN (US) 2002-09-12 WO disclosed
WO-2002058469-A1 PESTICIDAL COMPOUNDS AND COMPOSITIONS VAN BEEK, RON (US) 2002-08-01 WO disclosed
EP-1207865-A1 COMPOSITION FOR TREATMENT OF INFECTIONS OF HUMANS AND ANIMALS Van Beek Global/Ninkov L.L.C. (US) 2002-05-29 EP disclosed
WO-2001059008-A1 PETROLEUM ASPHALTS MODIFIED BY LIQUEFIED BIOMASS ADDITIVES WASTE TECHNOLOGY TRANSFER, INC. (US) 2001-08-16 WO disclosed
US-6258854-B1 KETONE ETHERS FOR ODORS GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) 2001-07-10 US disclosed
WO-2001015680-A1 COMPOSITION FOR TREATMENT OF INFECTIONS OF HUMANS AND ANIMALS VAN BEEK GLOBAL/NINKOV L.L.C. (US) 2001-03-08 WO disclosed
WO-2000013690-A1 EXOCYCLIC-PHOSPHOETHANOLAMINES CLARION PHARMACEUTICALS, INC. (US) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117370-A1 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS CYP2B6, TYR, CYP2D6 CNR1 1446/4885CNR2 1150/4885HTT 3738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.