Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105765 | 0.84 | KAT6A (0.47) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL299924 | 0.83 | MAPT (0.46) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL31529664 | 0.83 | MAPT (0.46) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL22598511 | 0.82 | MAPT (0.44) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL11885442 | 0.82 | MAPT (0.44) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| Hydrogen Peroxide SCHEMBL1877668 | 0.79 | HDAC4 (0.58) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| Hydrogen Peroxide SCHEMBL28407249 | 0.79 | HDAC4 (0.58) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| Hydrogen Peroxide SCHEMBL315899 | 0.79 | HDAC4 (0.58) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL30444032 | 0.79 | RXRA (0.66) | RXRARXRBRXRGSMN1; SMN2MAPT | |
| SCHEMBL105264 | 0.79 | RXRA (0.66) | RXRARXRBRXRGSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |