Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053203 | 0.85 | PDE4B (0.34) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL13996402 | 0.81 | CA1 (0.44) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL12589684 | 0.79 | CA1 (0.53) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL597009 | 0.79 | CA1 (0.49) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053290 | 0.77 | CA1 (0.31) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053224 | 0.76 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL500368 | 0.76 | CA1 (0.59) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL5583511 | 0.76 | CA1 (0.59) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL500078 | 0.75 | CA1 (0.53) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053207 | 0.73 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |