Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597009 | 0.83 | CA1 (0.49) | CA1CA2PRKCIENPP2CHRNB4 | |
| SCHEMBL10053283 | 0.81 | PDE4A (0.38) | CA1CA2CA9CA12TSHR | |
| SCHEMBL10053203 | 0.78 | PDE4B (0.34) | CA1CA2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10053282 | 0.78 | PDE4A (0.34) | CA1CA2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL500078 | 0.77 | CA1 (0.53) | CA1CA2CA9CA12CA4 | |
| SCHEMBL14001035 | 0.77 | CA1 (0.43) | CA1CA2CA9CA12 | |
| SCHEMBL10053280 | 0.77 | CA1 (0.43) | CA1CA2CA9CA12TSHR | |
| SCHEMBL500424 | 0.77 | CA1 (0.43) | CA1CA2CA9CA12TSHR | |
| SCHEMBL500341 | 0.77 | CA1 (0.43) | CA1CA2CA9CA12 | |
| SCHEMBL596084 | 0.75 | PDE4B (0.44) | CA1CA2TSHRENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465836-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465836-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |