Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15783212 | 0.97 | SIGMAR1 (0.44) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL5386253 | 0.95 | SIGMAR1 (0.43) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL15435142 | 0.95 | SIGMAR1 (0.43) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL17693500 | 0.95 | SIGMAR1 (0.43) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL16596775 | 0.92 | SIGMAR1 (0.42) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL13854487 | 0.91 | TP53 (0.41) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL29627323 | 0.91 | SIGMAR1 (0.41) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL18900588 | 0.91 | SIGMAR1 (0.41) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL13358672 | 0.90 | SIGMAR1 (0.40) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 | |
| SCHEMBL22755873 | 0.90 | TSHR (0.42) | SIGMAR1NR1I2LMNAADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2469341-B1 | Image bearing member and image forming method, image forming apparatus, and process cartridge | RICOH CO LTD (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-8652717-B2 | Image bearing member and image forming method, image forming apparatus, and process cartridge using the same | RICOH COMPANY, LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-8652717-B2 | Image bearing member and image forming method, image forming apparatus, and process cartridge using the same | RICOH COMPANY, LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20120163860-A1 | IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME | RICOH COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20120163860-A1 | IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME | RICOH COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| EP-2469341-A1 | Image bearing member and image forming method, image forming apparatus, and process cartridge | Ricoh Company, Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |