Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 19/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19184227 | 0.97 | P2RX3 (0.60) | P2RX3P2RX2 | |
| SCHEMBL10055553 | 0.92 | P2RX3 (0.60) | P2RX3 | |
| SCHEMBL10055212 | 0.90 | P2RX3 (0.59) | P2RX3P2RX2KMO | |
| SCHEMBL19184011 | 0.90 | P2RX3 (0.59) | P2RX3KMO | |
| SCHEMBL10055473 | 0.90 | P2RX3 (0.57) | P2RX3P2RX2 | |
| SCHEMBL17590811 | 0.90 | P2RX3 (0.62) | P2RX3 | |
| SCHEMBL10056357 | 0.89 | P2RX3 (0.60) | P2RX3 | |
| SCHEMBL16315079 | 0.89 | P2RX3 (0.51) | P2RX3P2RX2 | |
| SCHEMBL15015886 | 0.88 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL15015887 | 0.88 | P2RX3 (0.58) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |