Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287035 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL17234225 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL17234221 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL17234149 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL17234150 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL23586947 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 | |
| SCHEMBL8823414 | 0.81 | SLC7A5 (0.50) | SLC7A5SLC1A2SLC1A3SLC1A1ALDH1A1 | |
| SCHEMBL31370390 | 0.81 | SLC7A5 (0.50) | SLC7A5SLC1A2SLC1A3SLC1A1ALDH1A1 | |
| SCHEMBL31370395 | 0.81 | SLC7A5 (0.50) | SLC7A5SLC1A2SLC1A3SLC1A1ALDH1A1 | |
| SCHEMBL28254962 | 0.79 | SLC7A5 (0.48) | SLC7A5SLC1A2SLC1A3SLC1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089212-A1 | SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |