Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3966683 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL1224331 | 1.00 | — | — | |
| Piperazine SCHEMBL1005658 | 1.00 | HIF1A (0.86) | — | |
| Bromide SCHEMBL6017046 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL28043140 | 0.94 | — | — | |
| Bromide SCHEMBL12004053 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL5370035 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL5370033 | 0.94 | — | — | |
| Piperazine SCHEMBL5380983 | 0.94 | — | — | |
| SCHEMBL7052601 | 0.93 | HIF1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250386747-A1 | TIN BASED PEROVSKITE FIELD EFFECT TRANSISTOR MEMORY AND METHOD OF MANUFACTURING SAME | POSTECH RES & BUSINESS DEV FOUND (KR) | 2025-12-18 | — | — | US | claimed |
| EP-4663645-A1 | TIN BASED PEROVSKITE FIELD EFFECT TRANSISTOR MEMORY AND METHOD OF MANUFACTURING SAME | POSTECH Research and Business Development Foundation (KR) | 2025-12-17 | — | — | EP | claimed |
| EP-2454327-B1 | COLOR-CHANGING MATERIALS AND MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION | KIMBERLY CLARK CO (US) | 2015-04-15 | — | — | EP | claimed |
| US-8273306-B2 | Color-changing materials and multiple component materials having a color-changing composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2012-09-25 | — | — | US | claimed |
| EP-2454327-A2 | COLOR-CHANGING MATERIALS AND MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION | Kimberly-Clark Worldwide, Inc. (US) | 2012-05-23 | — | — | EP | claimed |
| WO-2011007284-A2 | COLOR-CHANGING MATERIALS AND MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2011-01-20 | — | — | WO | claimed |
| US-20110015598-A1 | Color-Changing Materials And Multiple Component Materials Having A Color-Changing Composition | KIMBERLY-CLARK WORLDWIDE, INC. | 2011-01-20 | — | — | US | claimed |
| US-20250386747-A1 | TIN BASED PEROVSKITE FIELD EFFECT TRANSISTOR MEMORY AND METHOD OF MANUFACTURING SAME | POSTECH RES & BUSINESS DEV FOUND (KR) | 2025-12-18 | — | — | US | disclosed |
| EP-4663645-A1 | TIN BASED PEROVSKITE FIELD EFFECT TRANSISTOR MEMORY AND METHOD OF MANUFACTURING SAME | POSTECH Research and Business Development Foundation (KR) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024203772-A1 | METHOD FOR PRODUCING ALPHA-CYANOACRYLATE | 東亞合成株式会社 | 2024-10-03 | — | — | WO | disclosed |
| CN-102203095-A | Purine derivatives for the treatment of allergic, inflammatory and infectious diseases | SMITHKLINE BEECHAM CORP | 2011-09-28 | — | — | CN | disclosed |
| CN-100484934-C | Process for preparing substituted pyrimidines and pyrimidine derivatives as protein kinase inhibitors | VERTEX PHARMA CO LTD (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-101012200-A | Process for preparing substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinases | VERTEX PHARMA (US) | 2007-08-08 | — | — | CN | disclosed |
| CN-1675199-A | Process for preparing substituted pyrimidines and pyrimidine derivatives as protein kinase inhibitors | VERTEX PHARMA (US) | 2005-09-28 | — | — | CN | disclosed |
| US-4994462-A | N,N-Bis(nipecotyl)piperazines | RESEARCH CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4935459-A | Molding materials | ATOCHEM (FR) | 1990-06-19 | — | — | US | disclosed |
| US-4798830-A | TETRAHYDROQUINOLINE DERIVATIVES | RESEARCH CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4634709-A | PIPERIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| US-4443450-A | N,N*-BIS(NIPECOTYL) PIPERAZINE | RESEARCH CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |