SCHEMBL1005704

SCHEMBL1005704

C=C(CCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
TET2 Q6N021 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
HTT P42858 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005515 1.00 USP2 (0.35) USP2MAPTTSHRTET2L3MBTL1
SCHEMBL1005766 1.00 USP2 (0.35) USP2MAPTTSHRTET2L3MBTL1
SCHEMBL1005917 1.00 USP2 (0.35) USP2MAPTTSHRTET2L3MBTL1
SCHEMBL5494366 0.94 TET2 (0.33) TSHRTET2
SCHEMBL2968317 0.90 TSHR (0.37) USP2MAPTTSHRTET2
SCHEMBL1005480 0.90 TSHR (0.37) USP2MAPTTSHRTET2
SCHEMBL2976485 0.90 TSHR (0.37) USP2MAPTTSHRTET2
SCHEMBL5526626 0.90 TSHR (0.37) USP2MAPTTSHRTET2
SCHEMBL16240728 0.90 TSHR (0.37) USP2MAPTTSHRTET2
SCHEMBL5529391 0.89 TSHR (0.35) USP2MAPTTSHRTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238715-B2 Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-01-19 US disclosed
US-20140163133-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIMICROBIAL COMPOSITION OBTAINED BY POLYMERIZING THE POLYMERIZABLE COMPOSITION MENICON CO., LTD (JP) 2014-06-12 US disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
EP-2578244-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIBACTERIAL COMPOSITION OBTAINED BY POLYMERIZING SAME Nanyang Technological University (SG) 2013-04-10 EP disclosed
US-7989560-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-08-02 US disclosed
US-7868112-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-01-11 US disclosed
US-20100093951-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORPORATION (JP) 2010-04-15 US disclosed
US-20100063222-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION CHISSO CORPORATION (JP) 2010-03-11 US disclosed
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-7037954-B2 Ocular lens material MENICON CO., LTD. (JP) 2006-05-02 US disclosed
US-20050243273-A1 Photochromic contact lens having excellent discoloring characteristic MENICON CO., LTD. (JP) 2005-11-03 US disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed