SCHEMBL5494366

SCHEMBL5494366

C=C(CCCC(F)(F)C(F)(F)C(F)(F)C(F)F)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.33
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005766 0.94 USP2 (0.35) TET2TSHR
SCHEMBL1005917 0.94 USP2 (0.35) TET2TSHR
SCHEMBL1005515 0.94 USP2 (0.35) TET2TSHR
SCHEMBL1005704 0.94 USP2 (0.35) TET2TSHR
SCHEMBL1005511 0.90 TET2 (0.34) TET2KDM4ETSHRTDP1
SCHEMBL5529391 0.85 TSHR (0.35) TET2KDM4ETSHRTDP1
SCHEMBL5526626 0.83 TSHR (0.37) TET2KDM4ETSHRTDP1
SCHEMBL16240728 0.83 TSHR (0.37) TET2KDM4ETSHRTDP1
SCHEMBL2976485 0.83 TSHR (0.37) TET2KDM4ETSHRTDP1
SCHEMBL1005480 0.83 TSHR (0.37) TET2KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-20050243273-A1 Photochromic contact lens having excellent discoloring characteristic MENICON CO., LTD. (JP) 2005-11-03 US disclosed