SCHEMBL10057719

SCHEMBL10057719

CC(C)=CCNC(=O)C(=O)NCC=C(C)C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
FNTA P49354 6/20 0.38
FNTB P49356 4/20 0.38
PGGT1B P53609 3/20 0.38
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
TRPV1 Q8NER1 6/20 0.35
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051892 0.91 FNTA (0.37) TRPA1FNTAFNTBPGGT1BMTNR1A
SCHEMBL10050748 0.85 KDM4E (0.37) TRPA1FNTAFNTBPGGT1BMTNR1A
SCHEMBL18368987 0.85 TRPA1 (0.36) TRPA1FNTAFNTBPGGT1BMTNR1A
SCHEMBL1710037 0.85 TRPA1 (0.33) TRPA1FNTAFNTBPGGT1BMTNR1A
SCHEMBL12164625 0.84 EGLN1 (0.48) TRPA1FNTAFNTBPGGT1BMTNR1A
SCHEMBL28965679 0.83
SCHEMBL1694511 0.81
SCHEMBL2568549 0.80 TRPA1 (0.65) TRPA1FNTAFNTBPGGT1BTRPV1
SCHEMBL2568553 0.80 TRPA1 (0.65) TRPA1FNTAFNTBPGGT1BTRPV1
SCHEMBL2571319 0.80 TRPA1 (0.65) TRPA1FNTAFNTBPGGT1BTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11654443-B2 Mineral processing CIDRA MINERALS PROCESSING INC. (US) 2023-05-23 US disclosed
US-11654443-B2 Mineral processing CIDRA MINERALS PROCESSING INC. (US) 2023-05-23 US disclosed
US-20200316613-A1 Mineral Processing CIDRA MINERALS PROC INC (US) 2020-10-08 US disclosed
US-10603676-B2 Mineral processing CIDRA MINERALS PROCESSING INC. (US) 2020-03-31 US disclosed
US-9764529-B2 Composite articles and methods of producing same SYNTOR FINE CHEMICALS LIMITED (GB) 2017-09-19 US disclosed
US-9764529-B2 Composite articles and methods of producing same SYNTOR FINE CHEMICALS LIMITED (GB) 2017-09-19 US disclosed
US-20160114336-A1 MINERAL PROCESSING CIDRA MINERALS PROCESSING INC. (US) 2016-04-28 US disclosed
US-20160114336-A1 MINERAL PROCESSING CIDRA MINERALS PROCESSING INC. (US) 2016-04-28 US disclosed
US-20150283784-A1 COMPOSITE ARTICLES AND METHODS OF PRODUCING SAME SUBLINO LIMITED (GB) 2015-10-08 US disclosed
US-20150283784-A1 COMPOSITE ARTICLES AND METHODS OF PRODUCING SAME SUBLINO LIMITED (GB) 2015-10-08 US disclosed
EP-2046840-B9 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND NOVEL POLYMER SOLUTIONS LTD (GB) 2013-04-24 EP disclosed
WO-2012131375-A2 WINDOW FRAMES, STRUCTURAL ELEMENTS FOR A ROOFED CONSTRUCTION AND METHODS OF ASSEMBLING SAME NOVEL POLYMER SOLUTIONS LIMITED (GB) 2012-10-04 WO disclosed
EP-2046840-B1 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND NOVEL POLYMER SOLUTIONS LTD (GB) 2012-08-08 EP disclosed
WO-2012017234-A1 METHODS OF TREATING TEXTILE FIBRES NOVEL POLYMER SOLUTIONS LIMITED (GB) 2012-02-09 WO disclosed
WO-2012017233-A1 METHODS OF COATING A LOW SURFACE ENERGY SUBSTRATE NOVEL POLYMER SOLUTIONS LIMITED (GB) 2012-02-09 WO disclosed
US-7750062-B2 Method of producing a polymeric material, polymer, monomeric compound and method of preparing a monomeric compound NOVEL POLYMER SOLUTIONS LIMITED (GB) 2010-07-06 US disclosed
US-7750062-B2 Method of producing a polymeric material, polymer, monomeric compound and method of preparing a monomeric compound NOVEL POLYMER SOLUTIONS LIMITED (GB) 2010-07-06 US disclosed
US-20090156706-A1 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND SUBLINO LIMITED (GB) 2009-06-18 US disclosed
US-20090156706-A1 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND SUBLINO LIMITED (GB) 2009-06-18 US disclosed
WO-2008001102-A1 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND NOVEL POLYMER SOLUTIONS LIMITED (GB) 2008-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156706-A1 METHOD OF PRODUCING A POLYMERIC MATERIAL, POLYMER, MONOMERIC COMPOUND AND METHOD OF PREPARING A MONOMERIC COMPOUND CCR9, CBR3, CRKL TRPA1 4272/4885FNTA 3527/4885FNTB 2119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.