Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610150 | 1.00 | POLB (0.35) | POLBTP53TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16487141 | 0.79 | TP53 (0.32) | POLBTP53CYP2D6CYP2C19 | |
| SCHEMBL16487139 | 0.79 | TP53 (0.32) | POLBTP53CYP2D6CYP2C19 | |
| SCHEMBL17533124 | 0.76 | — | — | |
| SCHEMBL12295867 | 0.76 | — | — | |
| SCHEMBL4722759 | 0.76 | — | — | |
| SCHEMBL28719441 | 0.76 | CYP2D6 (0.41) | POLBTP53TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16164274 | 0.75 | TP53 (0.36) | TP53TAS1R3TAS1R1TAS1R2CYP2D6 | |
| SCHEMBL8222868 | 0.74 | DPP4 (0.37) | POLBTAS1R3TAS1R1TAS1R2CYP2D6 | |
| SCHEMBL14944967 | 0.74 | CA1 (0.53) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268607-A2 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | Cti Bio (KR) | 2011-01-05 | — | — | EP | disclosed |