Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487139 | 1.00 | TP53 (0.32) | TP53POLBCYP2D6CYP2C19 | |
| SCHEMBL610150 | 0.79 | POLB (0.35) | TP53POLBCYP2D6CYP2C19 | |
| SCHEMBL1005905 | 0.79 | POLB (0.35) | TP53POLBCYP2D6CYP2C19 | |
| SCHEMBL28719441 | 0.74 | CYP2D6 (0.41) | TP53POLBCYP2D6CYP2C19 | |
| SCHEMBL8777208 | 0.74 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL16492819 | 0.74 | CA1 (0.46) | CYP2D6 | |
| SCHEMBL18170195 | 0.73 | TAS1R3 (0.34) | TP53CYP2D6CYP2C19 | |
| SCHEMBL5351163 | 0.73 | TAS1R3 (0.34) | TP53CYP2D6CYP2C19 | |
| SCHEMBL25170149 | 0.72 | MLYCD (0.30) | — | |
| SCHEMBL16823439 | 0.72 | TP53 (0.40) | TP53POLBCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194358-A1 | LINEAR PEPTIDE ANTIBIOTCS | RQX PHARMACEUTICALS, INC. | 2016-07-07 | — | — | US | disclosed |
| EP-3033352-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015023898-A1 | LINEAR PEPTIDE ANTIBIOTCS | RQX PHARMACEUTICALS, INC. (US) | 2015-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194358-A1 | LINEAR PEPTIDE ANTIBIOTCS | ANPEP, NPEPPS, PEPD | TP53 1213/4885POLB 1989/4885CYP2D6 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.