⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133471 | 0.87 | — | — | |
| SCHEMBL6240556 | 0.79 | — | — | |
| SCHEMBL96153 | 0.73 | — | — | |
| SCHEMBL31336187 | 0.73 | — | — | |
| SCHEMBL13494863 | 0.69 | NCF1 (0.34) | — | |
| SCHEMBL20614479 | 0.67 | CA12 (0.45) | — | |
| SCHEMBL4622 | 0.67 | — | — | |
| SCHEMBL1221354 | 0.67 | — | — | |
| SCHEMBL10001930 | 0.67 | CA12 (0.45) | — | |
| SCHEMBL2123718 | 0.67 | CA12 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349584-A1 | PROCESS FOR PREPARING N-(5-(3-(7-(3-FLUOROPHENYL)-3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-INDAZOL-5-YL)PYRIDIN-3-YL)-3-METHYLBUTANAMIDE | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2017-12-07 | — | — | US | disclosed |
| US-9663533-B2 | Thieno[3,2-C]pyridin-4(5H)-ones as BET inhibitors | GLAXOSMITHKLINE LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160297832-A1 | THIENO[3,2-C]PYRIDIN-4(5H)-ONES AS BET INHIBITORS | GLAXOSMITHKLINE LLC | 2016-10-13 | — | — | US | disclosed |
| WO-2016100555-A1 | BORONIC ACID DERIVATIVES AND USES THEREOF | INCEPTION 4, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| US-8962670-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8637490-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130045949-A1 | ANTI-CANCER AGENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20120016118-A1 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | WYETH LLC (US) | 2012-01-19 | — | — | US | disclosed |
| US-7582755-B2 | Such as 2-amino-5-(5-cyano-1-methyl-1H-pyrrol-2-yl) benzoic acid methyl ester by reacting cyanopyrrole with coupling agent, reacting with anthranilic alcohol or anthranilic nitro alcohol to form cyanopyrrole substituted anthranilic alcohol or cyanopyrrole substituted anthranilic nitro alcohol, reducing | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090209715-A1 | Process for producing polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090209715-A1 | Process for producing polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| EP-1892258-A1 | PROCESS FOR PRODUCING POLYMER | Sumitomo Chemical Company, Limited (JP) | 2008-02-27 | — | — | EP | disclosed |