SCHEMBL10060122

SCHEMBL10060122

CC(=O)/C(=N/Nc1ccccc1Cl)C(=O)Nc1ccc(OCCO)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.48
MAPK1 P28482 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 6/20 0.43
GAA P10253 3/20 0.43
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
LMNA P02545 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
GFER P55789 2/20 0.42
RECQL P46063 1/20 0.42
POLB P06746 2/20 0.41
THRB P10828 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060207 0.88 MAPT (0.47) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL15338095 0.88 MAPT (0.61) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL13707244 0.86 MAPT (0.47) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL10060120 0.85 NPC1 (0.51) MAPTMAPK1NPC1RAB9AALDH1A1
SCHEMBL12998581 0.83 GFER (0.55) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL764915 0.77 MAPT (0.44) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL10060125 0.77 KDM4E (0.43) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL10060123 0.77 MAPT (0.46) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL15943552 0.76 MAPT (0.49) MAPTMAPK1NPC1RAB9AKDM4E
SCHEMBL764209 0.75 MAPT (0.43) MAPTMAPK1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904581-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-04-10 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7846992-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2010-12-07 US disclosed
US-7846992-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2010-12-07 US disclosed
US-7582151-B2 Pigment dispersion with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582151-B2 Pigment dispersion with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20080242776-A1 Pigment Dispersion with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-10-02 US disclosed
US-20080242776-A1 Pigment Dispersion with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-10-02 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080214705-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-04 US disclosed
US-20080214705-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-04 US disclosed
WO-2007006636-A2 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2007-01-18 WO disclosed
WO-2007006639-A2 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2007-01-18 WO disclosed
WO-2007006635-A2 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2007-01-18 WO disclosed