SCHEMBL10060123

SCHEMBL10060123

COC(=O)c1cc(N/N=C(/C(C)=O)C(=O)Nc2ccc(OCCO)cc2)cc(C(=O)OC)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.46
KDM4E B2RXH2 4/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 6/20 0.41
GAA P10253 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.38
PTPN11 Q06124 2/20 0.37
FAAH O00519 2/20 0.37
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15943550 0.96 MAPT (0.45) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL10061191 0.94 MAPT (0.42) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL10060125 0.85 KDM4E (0.43) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL15338095 0.83 MAPT (0.61) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL10060119 0.82 POLB (0.49) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL12299537 0.82 MAPT (0.47) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL13707248 0.82 GFER (0.51) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL10060207 0.77 MAPT (0.47) MAPTKDM4ERAB9ANPC1MAPK1
SCHEMBL15943553 0.77 ALDH1A1 (0.33) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL764915 0.77 MAPT (0.44) MAPTKDM4ERAB9ANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed