SCHEMBL10060722 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CPS1	P31327	2/20	0.44

▸	CNR1	P21554	6/20	0.43

▸	HPGD	P15428	6/20	0.43

▸	TSHR	P16473	3/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	SMN1; SMN2	Q16637	3/20	0.36

▸	ROCK1	Q13464	1/20	0.36

▸	ALDH1A1	P00352	2/20	0.36

▸	POLB	P06746	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24746079	0.96	HPGD (0.48)	CPS1CNR1HPGDTSHRMAPT
SCHEMBL24745854	0.86	HPGD (0.46)	CNR1HPGDTSHRSMN1; SMN2ALDH1A1
SCHEMBL24745881	0.84	MEN1 (0.54)	CPS1HPGDTSHRMAPTALDH1A1
SCHEMBL24746242	0.84	HPGD (0.43)	CPS1CNR1HPGDTSHRALDH1A1
SCHEMBL24745853	0.83	MEN1 (0.53)	CPS1CNR1HPGDTSHRALDH1A1
SCHEMBL29891170	0.82	HPGD (0.42)	CPS1CNR1HPGDTSHRMAPT
SCHEMBL24746182	0.82	HPGD (0.42)	CPS1CNR1HPGDTSHRMAPT
SCHEMBL24746241	0.81	MEN1 (0.53)	CPS1CNR1HPGDTSHRALDH1A1
SCHEMBL24746431	0.81	SMN1; SMN2 (0.48)	HPGDTSHRSMN1; SMN2ALDH1A1
SCHEMBL22041286	0.81	MEN1 (0.47)	HPGDTSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012086735-A1	CONDENSED HETEROCYCLIC COMPOUND	大正製薬株式会社 (JP)	2012-06-28	—	—	WO	disclosed