Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24746242 | 0.95 | HPGD (0.43) | HPGDKMT2AMEN1L3MBTL3L3MBTL1 | |
| SCHEMBL24746079 | 0.90 | HPGD (0.48) | HPGDKMT2AMEN1CNR1ALDH1A1 | |
| SCHEMBL31464632 | 0.86 | PARP1 (0.38) | KMT2AMEN1L3MBTL3L3MBTL1CNR1 | |
| SCHEMBL10060722 | 0.86 | CPS1 (0.44) | HPGDCNR1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL24745853 | 0.85 | MEN1 (0.53) | HPGDKMT2AMEN1CNR1ALDH1A1 | |
| SCHEMBL29891170 | 0.84 | HPGD (0.42) | HPGDKMT2AMEN1L3MBTL3L3MBTL1 | |
| SCHEMBL24746182 | 0.84 | HPGD (0.42) | HPGDKMT2AMEN1L3MBTL3L3MBTL1 | |
| SCHEMBL31464596 | 0.83 | POLB (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24745881 | 0.83 | MEN1 (0.54) | HPGDKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL24746241 | 0.82 | MEN1 (0.53) | HPGDKMT2AMEN1CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |