Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871576 | 0.89 | HTT (0.59) | HTTUSP2PLA2G2CSPHK1PRKD3 | |
| SCHEMBL19839888 | 0.89 | HTT (0.59) | HTTUSP2PLA2G2CSPHK1PRKD3 | |
| SCHEMBL25955250 | 0.89 | HTT (0.59) | HTTUSP2PLA2G2CSPHK1PRKD3 | |
| SCHEMBL28427984 | 0.88 | HTT (0.46) | HTTPLA2G1BPLA2G2ASPHK1TLR2 | |
| SCHEMBL8187897 | 0.88 | HTT (0.46) | HTTPLA2G1BPLA2G2ASPHK1TLR2 | |
| Hydrochloric Acid SCHEMBL11302435 | 0.87 | HTT (0.57) | HTTUSP2PLA2G2CSPHK1TLR2 | |
| SCHEMBL15941723 | 0.86 | PLA2G1B (0.43) | HTTUSP2PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL25411331 | 0.85 | ALDH1A1 (0.48) | — | |
| SCHEMBL899581 | 0.85 | ALDH1A1 (0.48) | — | |
| SCHEMBL899325 | 0.85 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044638-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |