Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395908 | 0.82 | KDM4E (0.42) | KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL30952807 | 0.81 | KDM4E (0.36) | KDM4EL3MBTL1 | |
| SCHEMBL6343666 | 0.80 | KDM4E (0.50) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL537457 | 0.79 | KDM4E (0.44) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL1012734 | 0.75 | PTGS1 (0.63) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL15209248 | 0.74 | KDM4E (0.47) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL20028176 | 0.73 | KLKB1 (0.53) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL20028177 | 0.72 | KLKB1 (0.46) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL13014987 | 0.72 | PTGS2 (0.49) | KDM4EL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL824603 | 0.72 | CYP1A2 (0.56) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121261-A1 | INSECTICIDAL COMPOUND BASED ON PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-13 | — | — | WO | disclosed |
| EP-2125789-B1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2275422-A1 | Pyrimidinylpyrazoles as insecticide and parasiticide agents | Bayer CropScience AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2125789-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077483-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | PIR, ITPA, DDT | KDM4E 2464/4885L3MBTL1 2853/4885MAPT 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.