Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077705 | 0.81 | MMP8 (1.00) | MMP8MMP13HDAC4HDAC1HDAC3 | |
| SCHEMBL12261585 | 0.81 | MMP8 (0.84) | MMP8MMP13HDAC4HDAC1HDAC3 | |
| SCHEMBL10061356 | 0.78 | BACE1 (0.49) | MMP8MMP9KMT2AMAPTNPC1 | |
| SCHEMBL10061363 | 0.78 | MMP8 (0.74) | MMP8MMP13HDAC4HDAC1HDAC3 | |
| SCHEMBL610551 | 0.74 | ESR1 (0.53) | KMT2ARAB9AMAOBTLR9 | |
| SCHEMBL610552 | 0.74 | ESR1 (0.53) | KMT2ARAB9AMAOBTLR9 | |
| SCHEMBL14606209 | 0.74 | TDP1 (0.52) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL16558599 | 0.73 | MMP8 (0.69) | MMP8MMP13HDAC4HDAC1HDAC3 | |
| SCHEMBL4575956 | 0.72 | MMP8 (0.63) | MMP8MMP13HDAC4HDAC1HDAC3 | |
| SCHEMBL4575959 | 0.72 | MMP8 (0.63) | MMP8MMP13HDAC4HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | MMP8 1650/4885MMP13 1776/4885HDAC4 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.