Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22817906 | 0.90 | FGFR1 (0.42) | PSMB5FGFR1CYP1A2MAPTPLAU | |
| Hydrochloric Acid SCHEMBL22817905 | 0.90 | FGFR1 (0.42) | PSMB5FGFR1CYP1A2MAPTPLAU | |
| SCHEMBL13341566 | 0.85 | CYP1A2 (0.47) | PSMB5FGFR1CYP1A2MAPTHPGD | |
| SCHEMBL10061376 | 0.82 | CYP2C9 (0.50) | CYP1A2MMP8MAPTHPGDHTT | |
| Hydrochloric Acid SCHEMBL30275700 | 0.81 | FGFR1 (0.40) | PSMB5FGFR1CYP1A2MAPTHPGD | |
| SCHEMBL10061353 | 0.79 | MMP8 (0.56) | CYP1A2MMP8MAPTHPGDHTT | |
| SCHEMBL10061389 | 0.79 | FGFR1 (0.42) | PSMB5FGFR1CYP1A2MAPTEGFR | |
| SCHEMBL10080276 | 0.77 | FGFR1 (0.63) | PSMB5FGFR1CYP1A2MAPTHPGD | |
| SCHEMBL10061383 | 0.74 | FGFR1 (0.58) | PSMB5FGFR1MAPTEGFRMEN1 | |
| SCHEMBL10061375 | 0.70 | CCR6 (0.40) | PSMB5FGFR1CYP1A2MAPTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | PSMB5 1264/4885FGFR1 4281/4885CYP1A2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.