Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | JUN | P05412 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079960 | 0.92 | MEN1 (0.72) | NFKB1MEN1KMT2AJUNMME | |
| SCHEMBL16382595 | 0.87 | MEN1 (0.81) | NFKB1MEN1KMT2AJUNMME | |
| SCHEMBL10061383 | 0.80 | FGFR1 (0.58) | NFKB1MEN1KMT2AJUNMME | |
| SCHEMBL17694651 | 0.78 | NFKB1 (0.58) | NFKB1MEN1KMT2AJUNMME | |
| Cyclovalone SCHEMBL1151847 | 0.78 | MEN1 (1.00) | NFKB1MEN1KMT2AJUNMME | |
| Cyclovalone SCHEMBL554417 | 0.78 | MEN1 (1.00) | NFKB1MEN1KMT2AJUNMME | |
| Cyclovalone SCHEMBL554418 | 0.78 | MEN1 (1.00) | NFKB1MEN1KMT2AJUNMME | |
| Cyclovalone SCHEMBL29929726 | 0.78 | MEN1 (1.00) | NFKB1MEN1KMT2AJUNMME | |
| SCHEMBL17694652 | 0.76 | NFKB1 (0.60) | NFKB1MEN1KMT2AJUNMME | |
| SCHEMBL13324431 | 0.74 | NFKB1 (0.83) | NFKB1MEN1KMT2AJUNMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | NFKB1 800/4885MEN1 4644/4885KMT2A 2495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.