SCHEMBL10061399

SCHEMBL10061399

C=C(CC(=O)O)C(=O)Oc1ccc(/C=C/C(=O)OC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.52
KDM4E B2RXH2 3/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
TYR P14679 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51
KMT2A Q03164 4/20 0.47
GSK3B P49841 1/20 0.47
PTPN1 P18031 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
TTR P02766 1/20 0.44
APP P05067 1/20 0.44
THRB P10828 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
JAK2 O60674 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10061390 0.89 MAPT (0.52) MAPTKDM4ECA12CA1CA2
SCHEMBL10061386 0.89 MAPT (0.52) MAPTKDM4ECA12CA1CA2
SCHEMBL14977968 0.87 THRB (0.51) KDM4ECA12CA1CA2TYR
SCHEMBL10061391 0.86 KDM4E (0.49) MAPTKDM4ECA12CA1CA2
SCHEMBL10061402 0.84 MAPT (0.47) MAPTKDM4ECA12CA1CA2
SCHEMBL10061454 0.84 MAPT (0.47) MAPTKDM4ECA12CA1CA2
SCHEMBL18409935 0.83 MAPT (0.57) MAPTKDM4ECA12CA1CA2
SCHEMBL7691349 0.83 MAPT (0.57) MAPTKDM4ECA12CA1CA2
SCHEMBL7691353 0.83 MAPT (0.57) MAPTKDM4ECA12CA1CA2
SCHEMBL7693377 0.80 MAPT (0.53) MAPTKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450517-B2 Photosensitive compound and its photosensitive polymer JNC CORPORATION (JP) 2013-05-28 US disclosed
US-8450517-B2 Photosensitive compound and its photosensitive polymer JNC CORPORATION (JP) 2013-05-28 US disclosed
US-20120165491-A1 PHOTOSENSITIVE COMPOUND AND ITS PHOTOSENSITIVE POLYMER CHISSO PETROCHEMICAL CORPORATION (JP) 2012-06-28 US disclosed
US-20120165491-A1 PHOTOSENSITIVE COMPOUND AND ITS PHOTOSENSITIVE POLYMER CHISSO PETROCHEMICAL CORPORATION (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165491-A1 PHOTOSENSITIVE COMPOUND AND ITS PHOTOSENSITIVE POLYMER CCNT1, CCNA1, PYM1 MAPT 530/4885KDM4E 1937/4885CA12 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.