SCHEMBL10062358

SCHEMBL10062358

O=c1c2cc(-c3cccc(-c4cccc5c4sc4ccccc45)c3)ccc2sc2ccc(-c3cccc(-c4cccc5c4sc4ccccc45)c3)cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
KDM4E B2RXH2 3/20 0.47
PRKDC P78527 5/20 0.46
ALDH1A1 P00352 4/20 0.43
MAPT P10636 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
PARP14 Q460N5 1/20 0.42
TNKS O95271 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
PIK3CD O00329 2/20 0.39
PIK3CB P42338 2/20 0.39
BRD4 O60885 1/20 0.39
PIK3CA P42336 1/20 0.39
MTOR P42345 1/20 0.39
PIK3CG P48736 1/20 0.39
KCNH2 Q12809 1/20 0.39
BRDT Q58F21 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5019865 0.99 ALOX5 (0.57) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL5019867 0.99 ALOX5 (0.57) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL5019913 0.97 ALOX5 (0.56) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL15216402 0.96 ALOX5 (0.62) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL14410439 0.91 ALOX5 (0.64) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL17057253 0.89 ALOX5 (0.61) ALOX5PRKDCALDH1A1MAPTRAB9A
SCHEMBL17057267 0.89 ALOX5 (0.61) ALOX5PRKDCALDH1A1MAPTRAB9A
SCHEMBL15855437 0.88 ALOX5 (0.60) ALOX5KDM4EPRKDCALDH1A1MAPT
SCHEMBL17057268 0.87 ALOX5 (0.62) ALOX5PRKDCMAPTPARP14TNKS
SCHEMBL17057189 0.87 ALOX5 (0.62) ALOX5PRKDCMAPTPARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
WO-2012063751-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-18 WO disclosed