Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974948 | 0.92 | FFAR1 (0.48) | MRGPRX4PPARDPPARAFFAR1PPARG | |
| SCHEMBL2742880 | 0.88 | FFAR1 (0.49) | PPARDPPARAFFAR1 | |
| SCHEMBL10064429 | 0.83 | FFAR1 (0.50) | MRGPRX4PPARDPPARAFFAR1PPARG | |
| SCHEMBL2890794 | 0.81 | MRGPRX4 (0.46) | MRGPRX4PPARDPPARAFFAR1PPARG | |
| SCHEMBL231275 | 0.81 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL231516 | 0.75 | MRGPRX4 (0.47) | MRGPRX4 | |
| SCHEMBL10078102 | 0.74 | PPARA (0.60) | MRGPRX4PPARDPPARAFFAR1PPARG | |
| SCHEMBL10077179 | 0.73 | FFAR1 (0.51) | MRGPRX4PPARDPPARAFFAR1 | |
| SCHEMBL230898 | 0.73 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL2890248 | 0.72 | FFAR1 (0.53) | MRGPRX4PPARDPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |