Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974948 | 0.92 | FFAR1 (0.48) | FFAR1PPARDPPARAPPARGMRGPRX4 | |
| SCHEMBL10064988 | 0.88 | FFAR1 (0.52) | FFAR1PPARDPPARGFFAR4 | |
| SCHEMBL3036390 | 0.87 | FFAR1 (0.53) | FFAR1PPARDPPARAPPARGFFAR4 | |
| SCHEMBL230898 | 0.86 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL10078102 | 0.85 | PPARA (0.60) | FFAR1PPARDPPARAPPARGMRGPRX4 | |
| SCHEMBL10064688 | 0.85 | FFAR1 (0.46) | FFAR1PPARDPPARGFFAR4 | |
| SCHEMBL3035594 | 0.84 | FFAR1 (0.46) | FFAR1PPARDPPARAPPARGMRGPRX4 | |
| SCHEMBL3013876 | 0.84 | FFAR1 (0.50) | FFAR1PPARDPPARGFFAR4 | |
| SCHEMBL10064428 | 0.83 | MRGPRX4 (0.41) | FFAR1PPARDPPARAPPARGMRGPRX4 | |
| SCHEMBL2890248 | 0.83 | FFAR1 (0.53) | FFAR1PPARDPPARAMRGPRX4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |