⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010079 | 0.65 | — | — | |
| SCHEMBL11879958 | 0.63 | — | — | |
| SCHEMBL15572809 | 0.63 | — | — | |
| SCHEMBL22494208 | 0.63 | — | — | |
| SCHEMBL9663668 | 0.63 | P2RX7 (0.30) | — | |
| SCHEMBL9299549 | 0.62 | — | — | |
| SCHEMBL8953661 | 0.62 | — | — | |
| Amitrole SCHEMBL788110 | 0.62 | HSP90AA1 (0.33) | — | |
| SCHEMBL16673433 | 0.62 | — | — | |
| SCHEMBL10531111 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | claimed |
| US-6576628-B1 | Matrix metalloprotease inhibitors; arthritis, corneal ulcers, arteriosclerosis | ROCHE DIAGNOSTICS GMBH (DE) | 2003-06-10 | — | — | US | claimed |
| CN-110799190-B | Heterocyclic compounds | 卡都瑞恩医药有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |
| US-11197858-B2 | Substituted amines for treating cardiac diseases | CARDURION PHARMACEUTICALS, LLC (US) | 2021-12-14 | — | — | US | disclosed |
| EP-3444238-B1 | PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS | SATO PHARMA (JP) | 2021-12-08 | — | — | EP | disclosed |
| US-20210284627-A1 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2021-09-16 | — | — | US | disclosed |
| EP-3766877-A1 | INDOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-20200255408-A1 | INDOLE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2020-08-13 | — | — | US | disclosed |
| US-20200230137-A1 | SUBSTITUTED AMINES FOR TREATING CARDIAC DISEASES | CARDURION PHARMACEUTICALS, LLC (US) | 2020-07-23 | — | — | US | disclosed |
| EP-1243580-A1 | HETEROCYCLIC IMINO COMPOUNDS AND FUNGICIDES AND INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | Nissan Chemical Industries, Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-1180765-A1 | Optical recording medium and porphycene compound | Mitsui Chemicals, Inc. (JP) | 2002-02-20 | — | — | EP | disclosed |
| WO-1997011075-A1 | TRIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |
| EP-0305939-B1 | Process of producing sulfonylurea derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| US-4994571-A | Reacting heterocycle-containing sulfonamide compound with carbonyl compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0305939-A1 | Process of producing sulfonylurea derivatives | Takeda Chemical Industries, Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |