Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232116 | 0.89 | FFAR1 (0.41) | FFAR1LIPEL3MBTL1LMNACYP2C9 | |
| SCHEMBL232131 | 0.85 | FFAR1 (0.58) | FFAR1CYP2C9 | |
| SCHEMBL2966453 | 0.82 | FFAR1 (0.50) | FFAR1CMKLR1TSHR | |
| SCHEMBL2970621 | 0.81 | FFAR1 (0.53) | FFAR1TSHR | |
| SCHEMBL10064540 | 0.80 | FFAR1 (0.47) | FFAR1CMKLR1TSHR | |
| SCHEMBL16520013 | 0.80 | LMNA (0.36) | FFAR1MAPTLIPEL3MBTL1LMNA | |
| SCHEMBL2946459 | 0.80 | FFAR1 (0.54) | FFAR1L3MBTL1CMKLR1TSHR | |
| SCHEMBL16500076 | 0.80 | FFAR1 (0.40) | FFAR1L3MBTL1 | |
| SCHEMBL3012667 | 0.78 | FFAR1 (0.48) | FFAR1L3MBTL1LMNATSHR | |
| SCHEMBL3036390 | 0.78 | FFAR1 (0.53) | FFAR1CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |