Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064947 | 0.89 | HTT (0.56) | HSD11B1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10064819 | 0.89 | ITGB1 (0.42) | HSD11B1HTTGAAFFAR1ITGB1 | |
| SCHEMBL232020 | 0.88 | HSD11B1 (0.47) | HSD11B1HTTKDM4EALDH1A1GAA | |
| SCHEMBL15692433 | 0.87 | FFAR1 (0.47) | HSD11B1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10065073 | 0.86 | NPSR1 (0.49) | HSD11B1HTTFFAR1ITGB1ITGA4 | |
| SCHEMBL2753631 | 0.86 | FFAR1 (0.51) | HSD11B1FFAR1 | |
| SCHEMBL10064941 | 0.85 | ITGB1 (0.46) | HTTFFAR1ITGB1ITGA4 | |
| SCHEMBL10065066 | 0.83 | HTT (0.56) | HSD11B1HTTKDM4EALDH1A1GAA | |
| SCHEMBL3162742 | 0.82 | KMT2A (0.51) | HTTALDH1A1GAAFFAR1LMNA | |
| SCHEMBL10065687 | 0.81 | HSD11B1 (0.46) | HSD11B1HTTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |