SCHEMBL1006535

SCHEMBL1006535

C=C(CCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.38
THRB P10828 1/20 0.36
TBXAS1 P24557 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6017090 1.00 TET2 (0.38) TET2THRBTBXAS1GBA1
SCHEMBL2979332 1.00 TET2 (0.38) TET2THRBTBXAS1GBA1
SCHEMBL346143 1.00 TET2 (0.38) TET2THRBTBXAS1GBA1
SCHEMBL1490384 1.00 TET2 (0.38) TET2THRBTBXAS1GBA1
SCHEMBL968005 1.00 TET2 (0.38) TET2THRBTBXAS1GBA1
SCHEMBL347320 0.98 TET2 (0.39) TET2THRBTBXAS1
SCHEMBL9063878 0.93 TET2 (0.36) TET2THRBTBXAS1GBA1
SCHEMBL5525486 0.93 TET2 (0.40) TET2THRBTBXAS1
SCHEMBL3316604 0.90 TET2 (0.38) TET2THRB
SCHEMBL347265 0.90 TET2 (0.40) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238715-B2 Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-01-19 US disclosed
US-20140163133-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIMICROBIAL COMPOSITION OBTAINED BY POLYMERIZING THE POLYMERIZABLE COMPOSITION MENICON CO., LTD (JP) 2014-06-12 US disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
US-7989560-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-08-02 US disclosed
US-7868112-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-01-11 US disclosed
US-20100093951-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORPORATION (JP) 2010-04-15 US disclosed
US-20100063222-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION CHISSO CORPORATION (JP) 2010-03-11 US disclosed
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-7037954-B2 Ocular lens material MENICON CO., LTD. (JP) 2006-05-02 US disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed