Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL6011858 | 0.88 | ALDH1A1 (0.48) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL27783791 | 0.87 | ALDH1A1 (0.56) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL14718192 | 0.87 | ALDH1A1 (0.56) | ALDH1A1FKBP5 | |
| Sulfuric Acid SCHEMBL28002343 | 0.87 | ALDH1A1 (0.46) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL27464818 | 0.86 | ALDH1A1 (0.62) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL1971150 | 0.86 | ALDH1A1 (0.62) | ALDH1A1FKBP5 | |
| Sulfuric Acid SCHEMBL20972301 | 0.86 | ALDH1A1 (0.62) | ALDH1A1FKBP5 | |
| Sulfuric Acid SCHEMBL20972299 | 0.86 | ALDH1A1 (0.62) | ALDH1A1FKBP5 | |
| Sulfuric Acid SCHEMBL3670871 | 0.86 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Sulfuric Acid SCHEMBL573279 | 0.86 | ALDH1A1 (0.68) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200317976-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2020-10-08 | — | — | US | claimed |
| EP-3458539-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | Monash University (AU) | 2019-03-27 | — | — | EP | claimed |
| WO-2017197438-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2017-11-23 | — | — | WO | claimed |
| CN-108779143-A | Protein purification | UCB生物制药私人有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-107636012-A | Method of purifying protein | UCB生物制药私人有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107557810-A | A kind of Z-type hetero-junctions Cu2O_ graphenes _ α Fe2O3Nano-tube array photochemical catalyst and its preparation | 江西科技学院 | 2018-01-09 | — | — | CN | disclosed |
| US-20110033716-A1 | GAS-BARRIER COMPOSITION, COATING FILM, PROCESS FOR PRODUCING THE SAME, AND LAYERED MATERIAL | MITSUI CHEMICALS, INC. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-7879947-B2 | Gas-barrier composition, coating film and method for production of the same, and layered material | MITSUI CHEMICALS, INC. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-2277954-A1 | GAS BARRIER COMPOSITION, COATING FILM, METHOD FOR PRODUCING THE GAS BARRIER COMPOSITION, METHOD FOR PRODUCING THE COATING FILM, AND MULTILAYER BODY | Mitsui Chemicals, Inc. (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20090171003-A1 | Gas-barrier composition, coating film and method for production of the same, and layered material | MITSUI CHEMICALS, INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-7524900-B2 | Gas-barrier composition, coating film and method for production of the same, and layered material | MITSUI CHEMICALS, INC. (JP) | 2009-04-28 | — | — | US | disclosed |
| CN-100377406-C | Electrolyte material for fuel cell | TOYOTA MOTOR CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| EP-1894971-A1 | GAS BARRIER COMPOSITION, COATING FILM, METHODS FOR PRODUCING THOSE, AND MULTILAYER BODY | Mitsui Chemicals, Inc. (JP) | 2008-03-05 | — | — | EP | disclosed |
| US-20060293448-A1 | Gas-barrier composition, coating film and method for production of the same, and layered material | MITSUI CHEMICALS, INC. (JP) | 2006-12-28 | — | — | US | disclosed |
| CN-1788380-A | Electrolyte material for fuel cell | TOYOTA MOTOR CO LTD (JP) | 2006-06-14 | — | — | CN | disclosed |