SCHEMBL1006550

SCHEMBL1006550

CCS(=O)(=O)n1ccnc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
TP53 P04637 1/20 0.51
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
FABP4 P15090 1/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 1/20 0.39
HSD17B10 Q99714 2/20 0.37
NFKB1 P19838 1/20 0.37
QPCT Q16769 1/20 0.37
QPCTL Q9NXS2 1/20 0.37
TBXAS1 P24557 1/20 0.35
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25091028 0.85 HTT (0.50) HTTTP53TSHRMEN1KMT2A
SCHEMBL29008276 0.82 HTT (0.47) HTTTP53TSHRMEN1KMT2A
SCHEMBL5923834 0.80 HTT (0.53) HTTTP53TSHRMEN1KMT2A
SCHEMBL11979603 0.80 HTT (0.48) HTTTP53TSHRMEN1KMT2A
SCHEMBL27884358 0.77 HTT (0.46) HTTTP53TSHRMEN1KMT2A
SCHEMBL187487 0.76
SCHEMBL6300741 0.75 HTT (0.58) HTTTP53TSHRMEN1KMT2A
SCHEMBL1157477 0.75 HTT (0.58) HTTTP53TSHRMEN1KMT2A
SCHEMBL2089384 0.75 HTT (0.44) HTTTP53TSHRMEN1KMT2A
SCHEMBL25091130 0.75 HTT (0.44) HTTTP53TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101362755-B Sulfosulfuron preparation method JIANGSU AGROCHEM LAB 2012-01-11 CN claimed
CN-101362755-A Sulfosulfuron preparation method JIANGSU AGRICULTURAL HORMONE E (CN) 2009-02-11 CN claimed
EP-3883037-B1 ELECTROLYTE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME LG ENERGY SOLUTION LTD (KR) 2023-03-01 EP disclosed
EP-4136086-A1 TRICYCLIC PESTICIDAL COMPOUNDS BASF SE (DE) 2023-02-22 EP disclosed
EP-4061815-A1 PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS BASF SE (DE) 2022-09-28 EP disclosed
WO-2016172631-A2 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-10-27 WO disclosed
CN-101230113-B Sulfonyl grafted heterocycle materials for proton conducting electrolytes TOYOTA MOTOR ENGINERING & MFG NORTH AMERICA INC 2013-05-22 CN disclosed
US-8263563-B2 Furin inhibitors Smith, Robert E. (US) 2012-09-11 US disclosed
US-8263563-B2 Furin inhibitors Smith, Robert E. (US) 2012-09-11 US disclosed
US-8188284-B2 2-aminoquinolines HOFFMAN-LA ROCHE INC. (US) 2012-05-29 US disclosed
CN-101362755-B Sulfosulfuron preparation method JIANGSU AGROCHEM LAB 2012-01-11 CN disclosed
US-20090171003-A1 Gas-barrier composition, coating film and method for production of the same, and layered material MITSUI CHEMICALS, INC. (JP) 2009-07-02 US disclosed
US-20090131328-A1 FURIN INHIBITORS SMITH ROBERT E 2009-05-21 US disclosed
US-20090131328-A1 FURIN INHIBITORS SMITH ROBERT E 2009-05-21 US disclosed
US-7524900-B2 Gas-barrier composition, coating film and method for production of the same, and layered material MITSUI CHEMICALS, INC. (JP) 2009-04-28 US disclosed
CN-101362755-A Sulfosulfuron preparation method JIANGSU AGRICULTURAL HORMONE E (CN) 2009-02-11 CN disclosed
CN-101230113-A Sulfonyl grafted heterocycle materials for proton conducting electrolytes TOYOTA MOTOR ENGINERING & MFG (US) 2008-07-30 CN disclosed
US-20080152985-A1 SULFONYL GRAFTED HETEROCYCLE MATERIALS FOR PROTON CONDUCTING ELECTROLYTES Toyota Engineering & Manufacturing North America, Inc. (US) 2008-06-26 US disclosed
EP-1894971-A1 GAS BARRIER COMPOSITION, COATING FILM, METHODS FOR PRODUCING THOSE, AND MULTILAYER BODY Mitsui Chemicals, Inc. (JP) 2008-03-05 EP disclosed
US-20060293448-A1 Gas-barrier composition, coating film and method for production of the same, and layered material MITSUI CHEMICALS, INC. (JP) 2006-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131328-A1 FURIN INHIBITORS FURIN, PREP, TMPRSS15 HTT 3952/4885TP53 592/4885TSHR 2213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.