SCHEMBL10065682

SCHEMBL10065682

CC#CC(CC(=O)O)c1ccc(NC(=O)C(CC)Oc2cccc(C(C)(C)C)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.68
GNA15 P30679 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232545 0.89 FFAR1 (0.70) FFAR1
SCHEMBL15086757 0.81 FFAR1 (1.00) FFAR1
SCHEMBL15086767 0.81 FFAR1 (1.00) FFAR1
SCHEMBL15065084 0.81 FFAR1 (1.00) FFAR1
SCHEMBL2753691 0.80 FFAR1 (0.58) FFAR1
SCHEMBL225874 0.78 FFAR1 (0.69) FFAR1GNA15
SCHEMBL223214 0.78 FFAR1 (0.57) FFAR1GNA15
SCHEMBL223207 0.77 FFAR1 (0.70) FFAR1GNA15
SCHEMBL223514 0.77 FFAR1 (0.74) FFAR1GNA15
SCHEMBL2752966 0.77 POLB (0.52) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2590931-B1 (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENT SANOFI SA (FR) 2014-04-30 EP disclosed
WO-2012004269-A1 (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS SANOFI (FR) 2012-01-12 WO disclosed