SCHEMBL232545

SCHEMBL232545

CC#CC(CC(=O)O)c1ccc(NC(=O)C(C)Oc2cccc(C(C)(C)C)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.70
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2753691 0.91 FFAR1 (0.58) FFAR1
SCHEMBL10065682 0.89 FFAR1 (0.68) FFAR1
SCHEMBL15692463 0.88 FFAR1 (0.56) FFAR1TSHR
SCHEMBL2751966 0.87 FFAR1 (0.54) FFAR1TSHR
SCHEMBL231688 0.87 FFAR1 (0.54) FFAR1TSHR
SCHEMBL2752658 0.86 FFAR1 (0.64) FFAR1TSHR
SCHEMBL10065062 0.86 FFAR1 (0.62) FFAR1TSHR
SCHEMBL2753726 0.84 FFAR1 (0.59) FFAR1
SCHEMBL15692461 0.84 FFAR1 (0.53) FFAR1
SCHEMBL231684 0.83 FFAR1 (0.52) FFAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2590931-B1 (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENT SANOFI SA (FR) 2014-04-30 EP disclosed
US-8648038-B2 (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments SANOFI (FR) 2014-02-11 US disclosed
US-8648038-B2 (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments SANOFI (FR) 2014-02-11 US disclosed
US-8648038-B2 (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments SANOFI (FR) 2014-02-11 US disclosed
US-20120004167-A1 (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS SANOFI (FR) 2012-01-05 US disclosed
US-20120004167-A1 (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS SANOFI (FR) 2012-01-05 US disclosed
US-20120004167-A1 (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS SANOFI (FR) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004167-A1 (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS GPR119, DPP9, DPP7 FFAR1 96/4885TSHR 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.