Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.60 |
| ▸ | ACE | P12821 | 8/20 | 0.60 |
| ▸ | CPA1 | P15085 | 7/20 | 0.60 |
| ▸ | MMP2 | P08253 | 5/20 | 0.58 |
| ▸ | MMP9 | P14780 | 3/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.58 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.56 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468451 | 0.90 | MME (0.59) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL2782953 | 0.90 | MME (0.59) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL468452 | 0.90 | MME (0.59) | MMEACE2ACECPA1MMP2 | |
| Hydrochloric Acid SCHEMBL4853154 | 0.89 | MME (0.57) | MMEACE2ACECPA1MMP2 | |
| Hydrochloric Acid SCHEMBL4853148 | 0.89 | MME (0.57) | MMEACE2ACECPA1MMP2 | |
| Hydrochloric Acid SCHEMBL11661899 | 0.89 | MME (0.57) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL7387218 | 0.85 | MME (0.82) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL4960292 | 0.85 | MME (0.67) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL14885618 | 0.85 | ITGB1 (0.50) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL7900074 | 0.84 | MME (0.63) | MMEACE2ACECPA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181175-B2 | Process for manufacture and resolution of 2-acylamino-3-diphenylpropanoic acid | Zhejiang Jiuzhous Pharmaceutical Co., Ltd. (CN) | 2015-11-10 | — | — | US | disclosed |
| US-20140179947-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-06-26 | — | — | US | disclosed |
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | NOVARTIS AG (CH) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179947-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | DNPEP, MME, DPP7 | MME 2/4885ACE2 79/4885ACE 29/4885 |
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | DNPEP, MME, DPP7 | MME 2/4885ACE2 79/4885ACE 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.