Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065929 | 0.85 | CYP19A1 (0.37) | DPP4BAZ2BBAZ2AGRM4CHRNE | |
| SCHEMBL764212 | 0.82 | — | — | |
| SCHEMBL25615489 | 0.80 | — | — | |
| SCHEMBL16978921 | 0.80 | — | — | |
| SCHEMBL20624124 | 0.80 | — | — | |
| SCHEMBL12387660 | 0.80 | — | — | |
| SCHEMBL16978920 | 0.80 | — | — | |
| SCHEMBL21449851 | 0.80 | — | — | |
| SCHEMBL13469511 | 0.78 | SMPD1 (0.44) | DPP4 | |
| SCHEMBL2628202 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586542-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8222291-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20120082640-A1 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. | 2012-04-05 | — | — | US | disclosed |
| US-7807699-B2 | Dimeric pyrrolidine amide-containing small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080051389-A1 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | BID, BAD, BAX | DPP4 3556/4885BAZ2B 47/4885BAZ2A 41/4885 |
| US-20080051389-A1 | Small molecule apoptosis promoters | BID, BAD, BAX | DPP4 3556/4885BAZ2B 47/4885BAZ2A 41/4885 |
| US-20120082640-A1 | Small molecule apoptosis promoters | BID, BAD, BAX | DPP4 3556/4885BAZ2B 47/4885BAZ2A 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.