⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934464 | 0.87 | SMPD1 (0.45) | — | |
| SCHEMBL16526395 | 0.85 | SMPD1 (0.51) | — | |
| SCHEMBL14289745 | 0.84 | SMPD1 (0.54) | — | |
| SCHEMBL16263567 | 0.84 | SMPD1 (0.54) | — | |
| SCHEMBL13469511 | 0.82 | SMPD1 (0.44) | — | |
| SCHEMBL764212 | 0.81 | — | — | |
| SCHEMBL595044 | 0.80 | — | — | |
| SCHEMBL255391 | 0.80 | — | — | |
| SCHEMBL12386819 | 0.80 | — | — | |
| SCHEMBL10065962 | 0.78 | DPP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| WO-2024044810-A1 | NITRIFICATION INHIBITORS | THE UNIVERSITY OF MELBOURNE (AU) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024020164-A2 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| US-20240018583-A1 | METHOD FOR ANALYZING HIGHER-ORDER STRUCTURE OF RNA | XFOREST THERAPEUTICS CO., LTD. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-11833229-B2 | Labeling precursors with squaric acid coupling | SCV SPEZIAL-CHEMIKALIEN-VERTRIEBS GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| WO-2023222762-A1 | N6-ADENOSINE-METHYLTRANSFERASE PROTACS AND METHODS OF USE THEREOF | UNIVERSITY OF ZURICH (CH) | 2023-11-23 | — | — | WO | disclosed |
| EP-4230222-A1 | COMBINATION THERAPY WITH AN ANTI-AXL ANTIBODY-PBD CONJUGATE AND NANOCUPS | Oxsonics Limited (GB) | 2023-08-23 | — | — | EP | disclosed |
| US-20230220008-A1 | MULTIMERIC BICYCLIC PEPTIDE LIGANDS | BICYCLETX LIMITED (GB) | 2023-07-13 | — | — | US | disclosed |
| US-20220194904-A1 | 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS | CORNELL UNIVERSITY (US) | 2022-06-23 | — | — | US | disclosed |
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| US-20110207767-A1 | Novel cc-1065 Analogs and Their Conjugates | BYONDIS B.V. (NL) | 2011-08-25 | — | — | US | disclosed |
| US-20100267596-A1 | METHOD FOR IMPROVING THE HYDROLYSIS STABILITY OF IONIC LIQUIDS | BASE SE (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2229365-A1 | METHOD FOR IMPROVING THE HYDROLYSIS STABILITY OF IONIC LIQUIDS | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-20100093720-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR TREATMENT OF GASTROINTESTINAL DYSMOTILITY DISORDERS | MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED (IE) | 2010-04-15 | — | — | US | disclosed |
| US-7692030-B2 | Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer | UNIVERSITY OF WASHINGTON (US) | 2010-04-06 | — | — | US | disclosed |
| US-7692030-B2 | Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer | UNIVERSITY OF WASHINGTON (US) | 2010-04-06 | — | — | US | disclosed |
| WO-2009077452-A1 | METHOD FOR IMPROVING THE HYDROLYSIS STABILITY OF IONIC LIQUIDS | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |
| US-20080103192-A1 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | WASHINGTON, UNIVERSITY OF (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080103192-A1 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | WASHINGTON, UNIVERSITY OF (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008046109-A2 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITY OF WASHINGTON (US) | 2008-04-17 | — | — | WO | disclosed |