Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192279 | 0.92 | ESR1 (0.43) | ESR1ESR2KMT2AMEN1ALOX15 | |
| SCHEMBL823275 | 0.91 | ESR1 (0.40) | ESR1ESR2KMT2AMEN1ALOX15 | |
| SCHEMBL19750309 | 0.89 | ESR1 (0.43) | ESR1ESR2KMT2AMEN1NPSR1 | |
| SCHEMBL823264 | 0.87 | ESR1 (0.42) | ESR1ESR2ALDH1A1 | |
| SCHEMBL10065615 | 0.83 | ESR1 (0.40) | ESR1ESR2PDK2 | |
| SCHEMBL12346214 | 0.82 | ESR1 (0.41) | ESR1ESR2NPSR1PDK2 | |
| SCHEMBL18648920 | 0.82 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL13448621 | 0.82 | ESR1 (0.40) | ESR1ESR2PDK2 | |
| SCHEMBL14701779 | 0.82 | KMT2A (0.37) | ESR1ESR2KMT2AMEN1ALOX15 | |
| SCHEMBL18648958 | 0.81 | ESR1 (0.45) | ESR1ESR2KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2163922-B1 | OPTICAL FILM | TEIJIN CHEMICALS LTD (JP) | 2012-01-25 | — | — | EP | disclosed |