Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022582 | 0.85 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL10022608 | 0.81 | ROCK2 (0.82) | ROCK2 | |
| SCHEMBL10066400 | 0.81 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL10022600 | 0.80 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL10066564 | 0.79 | ROCK2 (0.72) | ROCK2 | |
| SCHEMBL10022614 | 0.79 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL10022595 | 0.79 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL323851 | 0.78 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL323850 | 0.78 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL324947 | 0.78 | ROCK2 (0.68) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006203-A1 | N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |