SCHEMBL10066252

SCHEMBL10066252

CCC[N+]1=C(/C=C/C=C2\SCCN2CC)C(C)(C)c2cc(Cl)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.44
FURIN P09958 1/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 2/20 0.43
RAB9A P51151 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
NR2F2 P24468 1/20 0.43
RUNX1 Q01196 1/20 0.43
CBFB Q13951 1/20 0.43
PTPN1 P18031 1/20 0.37
USP2 O75604 1/20 0.34
S1PR2 O95136 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066272 0.89 PRMT1 (0.40) PRMT1FURINMAPTMEN1NPC1
SCHEMBL10066266 0.88 PRMT1 (0.46) PRMT1FURINMAPTMEN1NPC1
SCHEMBL10066260 0.87 MAPT (0.46) PRMT1FURINMAPTMEN1NPC1
SCHEMBL15395224 0.81 FURIN (0.41) PRMT1FURINMAPTMEN1NPC1
SCHEMBL10066251 0.81 MAPT (0.49) PRMT1FURINMAPTMEN1NPC1
SCHEMBL16314540 0.80 MAPT (0.46) PRMT1FURINMAPTMEN1NPC1
SCHEMBL10052802 0.80 PRMT1 (0.42) PRMT1MAPTMEN1HTTKMT2A
SCHEMBL10052806 0.79 PRMT1 (0.40) PRMT1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL10052853 0.79 PRMT1 (0.38) PRMT1MAPTMEN1LMNAHTT
SCHEMBL10066264 0.78 PRMT1 (0.53) PRMT1FURINMAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206619-B2 Color correction material, film-forming composition, and optical filter ADEKA CORPORATION (JP) 2012-06-26 US disclosed
EP-2298838-A1 COLOR CORRECTION MATERIAL, FILM-FORMING COMPOSITION, AND OPTICAL FILTER Adeka Corporation (JP) 2011-03-23 EP disclosed
US-20110049446-A1 COLOR CORRECTION MATERIAL, FILM-FORMING COMPOSITION, AND OPTICAL FILTER ADEKA CORPORATION (JP) 2011-03-03 US disclosed