SCHEMBL10066264

SCHEMBL10066264

CCC[N+]1=C(/C=C/C=C2\SCCN2CC)C(C)(C)c2c1ccc1ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 11/20 0.53
PRMT5 O14744 1/20 0.47
PRMT8 Q9NR22 1/20 0.47
BLM P54132 2/20 0.42
FURIN P09958 1/20 0.42
MEN1 O00255 3/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
HTT P42858 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
NR2F2 P24468 1/20 0.41
RUNX1 Q01196 1/20 0.41
CBFB Q13951 1/20 0.41
THRB P10828 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066271 0.88 PRMT1 (0.42) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL15176865 0.88 PRMT1 (0.43) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL10066265 0.88 PRMT1 (0.48) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL10066260 0.83 MAPT (0.46) PRMT1BLMFURINMEN1LMNA
SCHEMBL15177226 0.79 PRMT1 (0.41) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL10066252 0.78 PRMT1 (0.44) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL10052798 0.78 PRMT1 (0.35) PRMT1PRMT5PRMT8MEN1LMNA
SCHEMBL10066251 0.77 MAPT (0.49) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL16314540 0.77 MAPT (0.46) PRMT1PRMT5PRMT8BLMFURIN
SCHEMBL10052799 0.77 PRMT1 (0.40) PRMT1PRMT5PRMT8BLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206619-B2 Color correction material, film-forming composition, and optical filter ADEKA CORPORATION (JP) 2012-06-26 US disclosed
US-20110049446-A1 COLOR CORRECTION MATERIAL, FILM-FORMING COMPOSITION, AND OPTICAL FILTER ADEKA CORPORATION (JP) 2011-03-03 US disclosed