SCHEMBL10066566

SCHEMBL10066566

C=C(OC1CCC2CC(COc3ccc(OCC)c(F)c3F)CCC2C1)c1ccc(CCC)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SCN9A Q15858 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9924808 0.88 USP2 (0.36) USP2NPSR1HSD17B10SCN9AFFAR4
SCHEMBL9924969 0.86 FFAR4 (0.38) USP2NPSR1HSD17B10SCN9AFFAR4
SCHEMBL9924941 0.83 USP2 (0.38) USP2NPSR1HSD17B10SCN9AFFAR4
SCHEMBL9925027 0.83 USP2 (0.36) USP2NPSR1HSD17B10SCN9AFFAR4
SCHEMBL9924811 0.83 SCN9A (0.33) SCN9AFFAR4
SCHEMBL9924806 0.82 FFAR4 (0.37) USP2NPSR1HSD17B10SCN9AFFAR4
SCHEMBL9924812 0.82 SSTR5 (0.35) SCN9AFFAR4
SCHEMBL19189742 0.81 FFAR4 (0.31) FFAR4
SCHEMBL9924940 0.80 MAOB (0.37) SCN9AFFAR4
SCHEMBL9924972 0.80 NAAA (0.36) SCN9AFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468707-A1 DECAHYDRONAPHTHALENE COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY ELEMENTS CONTAINING THE LIQUID CRYSTAL COMPOSITIONS JNC Corporation (JP) 2012-06-27 EP disclosed