Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857500 | 1.00 | CES2 (0.62) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL10745729 | 1.00 | CES2 (0.62) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL9873254 | 1.00 | CES2 (0.62) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL4300387 | 1.00 | CES2 (0.62) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL6887004 | 0.98 | CES2 (0.59) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL7139881 | 0.86 | CES2 (0.47) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL7135950 | 0.86 | CES2 (0.47) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL7132934 | 0.86 | CES2 (0.47) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL15282914 | 0.85 | KDM1A (0.47) | CES2POLBGMNNTP53MAPT | |
| SCHEMBL14972396 | 0.84 | TSHR (0.54) | CES2POLBGMNNTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178713-B2 | Sulfur-containing phospholipid derivatives | Pronovo Biopharma Norge AS (NO) | 2012-05-15 | — | — | US | disclosed |