SCHEMBL10067418

SCHEMBL10067418

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1Oc1ccc(OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 5/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
RARG P13631 6/20 0.51
RARA P10276 6/20 0.46
CYP26A1 O43174 3/20 0.46
RXRA P19793 5/20 0.44
RARB P10826 4/20 0.44
PTGS1 P23219 3/20 0.44
RXRB P28702 2/20 0.44
RXRG P48443 2/20 0.44
RORC P51449 2/20 0.44
CYP3A4 P08684 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
MAPK1 P28482 2/20 0.44
HTR2B P41595 2/20 0.44
BLM P54132 2/20 0.44
HIF1A Q16665 2/20 0.44
NR4A1 P22736 1/20 0.44
NR1H2 P55055 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3411832 1.00 ALDH1A1 (0.55) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL3411838 1.00 ALDH1A1 (0.55) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL3411829 1.00 ALDH1A1 (0.55) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL14519806 0.92 RARG (0.45) ALDH1A1MAPTSMN1; SMN2RARGCYP3A4
SCHEMBL13252678 0.89 RARG (0.45) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL1718771 0.83 ALDH1A1 (0.65) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL1718768 0.83 ALDH1A1 (0.65) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL3407633 0.83 MAPT (0.65) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL3407627 0.83 MAPT (0.65) ALDH1A1MAPTSMN1; SMN2RARGRARA
SCHEMBL3414609 0.82 ALDH1A1 (0.49) ALDH1A1MAPTSMN1; SMN2RARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1968993-B1 NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME FABRE PIERRE DERMO COSMETIQUE (FR) 2012-01-11 EP disclosed